A study linking popular weight loss drug to suicide risk again raises long-standing safety questions

Editor’s Note: If you or someone you know is struggling with suicidal thoughts or mental health matters, please call the 988 Suicide & Crisis Lifeline by dialing 988 to connect with a trained counselor, or visit the 988 Lifeline website.

People taking semaglutide, the popular medication for diabetes and weight loss, are more likely to report having thoughts of suicide compared with those taking other drugs, according to a new study of an international drug safety database. But the finding is the latest see-saw of scientific evidence on the risk of depression and suicide tied to the popular medications — and critics say evidence that the drugs cause problems with mood is limited.

A study linking popular weight loss drug to suicide risk again raises long-standing safety questions

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Ian Douglas, London School of Hygiene & Tropical Medicine:

I am an epidemiologist, currently funded by GlaxoSmithKline. I initially studied physiology at BSc and PhD level in Manchester. Since then, I spent several years at the UK Medicines & Healthcare Products Regulatory Agency and in the pharmaceutical industry investigating adverse effects of drugs – both in clinical trials and post-marketing. I completed the MSc in epidemiology at LSHTM in 2005.

Previously:

Medicare to cover obesity drugs, but not for weight loss

Wegovy, Rybelsus, and Ozempic, are the different brand names for Semaglutide. They have a black box warning for Medullary thyroid cancer.* 🤦🏼‍♀️

Related:

Wegovy side effects: What you should know

*Obesity and Cancer

Everything We Learned From Oprah’s Weight Loss Special

Mounjaro:

Using Mounjaro may increase your risk of developing thyroid cancer.

How Antidepressants Are Numbing More Than Depression

In our relentless pursuit to transcend the human suffering, we’ve stumbled into a dangerous oversimplification: an improved mental state reflects the absence or decrease in negative emotional states. This reductionist view has not only cheapened our understanding of the human emotional spectrum but has also paved the way for a troubling linguistic shift.

How Antidepressants Are Numbing More Than Depression

Who Really Controls US Foreign Policy?

YouTube / Rumble

From the ongoing US involvement in Ukraine, to an enduring US military presence in the Middle East, and growing US-Chinese tensions in the Asia-Pacific region, regardless of who controls the US Congress and regardless of who sits in the White House, these conflicts continue forward – often with a Democratic president setting the stage for his Republican successor, and vice versa. 

Who Really Controls US Foreign Policy? (archived)

The FDA Just Quietly Gutted Protections for Human Subjects in Research

Late last year, the U.S. Food and Drug Administration (FDA) quietly introduced a regulation that may be one of the most important shifts in how non-profit and for-profit U.S. institutions, both at home and abroad, conduct future medical and public health research. It represents an erosion of personal medical choice and threatens to undermine the public’s trust in scientific investigations in biomedicine.

The FDA Just Quietly Gutted Protections for Human Subjects in Research

Reuters Exposes Washington’s Global Disinformation Campaign: The Rest of the Story

In a recent article, Reuters confirms what many knew for years, that the United States government and its various departments and agencies have been conducting global disinformation campaigns targeting nations it seeks to undermine, and whose governments it seeks to overthrow.

Reuters Exposes Washington’s Global Disinformation Campaign: The Rest of the Story

Previously:

Philippines: Pentagon ran secret anti-vax campaign to undermine China during pandemic

Philippines: ACT solon wants to probe alleged US Pentagon secret anti-vax campaign

MANILA, Philippines — A lawmaker on Sunday called on the leaders of the House of Representatives to initiate a thorough probe into the alleged secret anti-inoculation campaign of the United States (US) military aimed at undermining China during the COVID-19 pandemic.

ACT solon wants to probe alleged US Pentagon secret anti-vax campaign (archived)

Previously:

Philippines: Pentagon ran secret anti-vax campaign to undermine China during pandemic

Chinese Company Under Congressional Scrutiny Makes Key U.S. Drugs

Source

Lawmakers raising national security concerns and seeking to disconnect a major Chinese firm from U.S. pharmaceutical interests have rattled the biotech industry. The firm is deeply involved in development and manufacturing of crucial therapies for cancer, cystic fibrosis, H.I.V. and other illnesses.

Chinese Company Under Congressional Scrutiny Makes Key U.S. Drugs

Latest:

US bill to restrict WuXi AppTec, Chinese biotechs revised to give more time to cut ties