A study linking popular weight loss drug to suicide risk again raises long-standing safety questions

Editor’s Note: If you or someone you know is struggling with suicidal thoughts or mental health matters, please call the 988 Suicide & Crisis Lifeline by dialing 988 to connect with a trained counselor, or visit the 988 Lifeline website.

People taking semaglutide, the popular medication for diabetes and weight loss, are more likely to report having thoughts of suicide compared with those taking other drugs, according to a new study of an international drug safety database. But the finding is the latest see-saw of scientific evidence on the risk of depression and suicide tied to the popular medications — and critics say evidence that the drugs cause problems with mood is limited.

A study linking popular weight loss drug to suicide risk again raises long-standing safety questions

Related:

Ian Douglas, London School of Hygiene & Tropical Medicine:

I am an epidemiologist, currently funded by GlaxoSmithKline. I initially studied physiology at BSc and PhD level in Manchester. Since then, I spent several years at the UK Medicines & Healthcare Products Regulatory Agency and in the pharmaceutical industry investigating adverse effects of drugs – both in clinical trials and post-marketing. I completed the MSc in epidemiology at LSHTM in 2005.

Previously:

Medicare to cover obesity drugs, but not for weight loss

Wegovy, Rybelsus, and Ozempic, are the different brand names for Semaglutide. They have a black box warning for Medullary thyroid cancer.* 🤦🏼‍♀️

Related:

Wegovy side effects: What you should know

*Obesity and Cancer

Everything We Learned From Oprah’s Weight Loss Special

Mounjaro:

Using Mounjaro may increase your risk of developing thyroid cancer.

The FDA Just Quietly Gutted Protections for Human Subjects in Research

Late last year, the U.S. Food and Drug Administration (FDA) quietly introduced a regulation that may be one of the most important shifts in how non-profit and for-profit U.S. institutions, both at home and abroad, conduct future medical and public health research. It represents an erosion of personal medical choice and threatens to undermine the public’s trust in scientific investigations in biomedicine.

The FDA Just Quietly Gutted Protections for Human Subjects in Research

Marx, Spinoza, and the Political Implications of Contemporary Psychiatry

Simple logic tells us that those atop a societal hierarchy will provide rewards for professionals—be they clergy or psychiatrists—who promote an ideology that maintains the status quo, and that the ruling class will do everything possible to manipulate the public to believe that the social-economic-political status quo is natural.

Marx, Spinoza, and the Political Implications of Contemporary Psychiatry

Indonesia’s feared ex-general Prabowo claims victory in presidential election + Notes

Indonesia’s feared ex-general Prabowo claims victory in presidential election

But the likely victory of Prabowo — an ex-general who was kicked out from the army and subjected to a two-decade ban from the U.S. over human rights violations — raises fears of the world’s third-largest democracy sliding backward into authoritarian rule.

Related:

3 things you should know about Indonesia’s presidential elections

Continuity and its risks


Prabowo is expected to largely continue the policies of President Widodo, or “Jokowi,” as Indonesians call him. President Widodo is not up for reelection as he’s serving his final term.

Through his two five-year terms, Indonesia’s economy — Southeast Asia’s largest — has grown at about 5% a year. His infrastructure building, cash and food assistance to the poor and health and education policies have been popular.

Indonesia is the world’s largest producer of nickel, used in making electric vehicle batteries, and Jokowi has barred the export of raw nickel, to help Indonesia move up the value chain from mining to manufacturing.

Prabowo is Suharto’s son-in-law. He received training in the 1980s from the U.S. military at Fort Benning, Ga. (now Fort Moore) and Fort Bragg, N.C. (now Fort Liberty).

Indonesia’s presidential election emerges as key battleground in US-China rivalry

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Millions of Dollars of Pharma Money Went to the DSM-5-TR Authors

Source: Talk World Radio: Bruce Levine on Psychiatry and Spinoza

About 60% of the authors had financial ties to industry, which are not disclosed in the DSM. Studies show that conflicts of interest lead to pro-industry decision-making.

Millions of Dollars of Pharma Money Went to the DSM-5-TR Authors

H/T: Unorthodox Truth

Previously:

Scientific Misconduct and Fraud: The Final Nail in Psychiatry’s Antidepressant Coffin