Pfizer’s anti-COVID pill Paxlovid shows no benefit for younger adults

Pfizer’s anti-COVID pill Paxlovid shows no benefit for younger adults

The report’s authors found that Pfizer’s antiviral medication Paxlovid offered little to no benefit for younger adults. However, it did reduce the risk of hospitalization for high-risk seniors. Notably, supplementary material from the original study of Paxlovid in high-risk non-hospitalized adults with COVID-19 during the Delta wave had demonstrated benefits in those younger than 65, albeit the difference compared to the placebo was much less than in those 65 and older.

Among those over 65, there was a 73 percent decrease in the hospitalization rate and a 79 percent reduction in the risk of death. However, patients between the ages of 40 and 65 saw no benefit in taking the antiviral medication in either category, regardless of previous immunity status.

Another critical study from Hong Kong published in Lancet Infectious Diseases on the same day as the Israeli study but which went unmentioned in the press offered further evidence of Paxlovid’s limited therapeutic role. The authors reviewed their clinical experience with Paxlovid and Lagevrio, Merck’s antiviral pill, Molnupiravir, in hospitalized patients. They compared them to hospitalized patients who did not receive those medications during the horrific wave of infections that slammed into the semi-autonomous region in February and March.

The mortality risk reduction for Lagevrio was 52 percent, and for Paxlovid it was 66 percent. Those receiving antivirals had a lower risk of their disease progressing, but the drugs did not significantly impact their need for mechanical ventilation or ICU admission. The patients in the study averaged in age from mid-70s to early 80s.

Given the results of these studies, it bears mentioning that the Centers for Disease Control and Prevention (CDC) has recently estimated that approximately 95 percent of Americans aged 16 and older have some level of immunity against COVID-19.

Bill Gates and the Secret Push to Save Biden’s Climate Bill

Bill Gates and the Secret Push to Save Biden’s Climate Bill

Gates started wooing Manchin and other senators who might prove pivotal for clean-energy policy in 2019 over a meal in Washington DC. “My dialogue with Joe has been going on for quite a while,” Gates said. “Almost everyone on the energy committee” — of which Manchin was then the senior-most Democrat — “came over and spent a few hours with me over dinner.”

Also at Manchin’s insistence, automakers also will see new strings attached to electric vehicle tax incentives so they will have to be made in North America and, by 2024, can’t use batteries sourced from China. Labor leaders bemoaned that the final package doesn’t contain much support for workers who lose their jobs in the green transition.

There’s been such whiplash from 2016 when, as Gates puts it, green spending from the US government “had dropped to near zero.” Six years later, American climate finance has been “reinvigorated,” and Gates now sees innovation “going way faster than I expected. That’s why I’m optimistic that we will solve this thing.”

The working class is going to be thrown under the bus, but at least Bill Gates is happy. 🤷🏼‍♀️

Here’s the Whole Transcript of That Leaked Steve Bannon Tape, Annotated

The Halloween 2020 meeting in which Steve Bannon explained that Donald Trump planned to declare victory on election night, regardless of the actual results, was not supposed to be a big deal. The gathering was intended for Bannon to help associates of his patron, exiled Chinese mogul Guo Wengui, plan election night coverage on GTV News, one of Guo’s media companies.

Here’s the Whole Transcript of That Leaked Steve Bannon Tape, Annotated

South African Minister Tells West To Stop “Patronising Bullying” On Ukraine

Minister Pandor made these statements while sitting next to U.S. Secretary of State Antony Blinken

South Africa’s Minister of International Relations and Cooperation Naledi Pandor has warned global powers against dictating how African countries should respond to global issues saying South Africa will never accept what she termed “patronising bullying”.

South African Minister Tells West To Stop “Patronising Bullying” On Ukraine

Related:

Blinken: US Won’t ‘Dictate Africa’s Choices’ on Russia, But…

In South Africa, Blinken has been pressed about legislation passed by the House this year that aims – in the words of its author, House Foreign Affairs Committee chairman Gregory Meeks (D-N.Y.) – to “counter the malign influence and activities of the Russian Federation and its proxies in Africa.”

The text describes Russia’s “malign influence and activities” as those “that undermine United States objectives and interests.” – i.e, US corporate interests!

Last week, Pandor offered pointed criticism of the legislation, describing it as an “unprecedented” measure that is “intended to punish countries in Africa that have not toed the line on the Russia-Ukraine war.”

The Countering Malign Russian Activities in Africa Act passed the House in April in a 415-9 vote, and now faces Senate consideration.

‘Offensive’

At a joint press briefing with Blinken on Monday, Pandor expressed the hope the Senate would reject the “offensive” bill.

“When we believe in freedom, as I’m saying, it’s freedom for everybody, you can’t say because Africa is doing this, you will then be punished by the United States,” she said.

Pandor argued that South Africa’s position on Ukraine was one of abhorring war and supporting a search for peace.

She also suggested that the U.S. employs double standards, by supporting freedom for Ukraine but not for the Palestinians.

“We should be equally concerned at what is happening to the people of Palestine as we are with what is happening to the people of Ukraine,” she said. “We’ve not seen an even-handed approach in the utilization of the prescripts of international law.”

In a television interview in Johannesburg earlier in the day, Blinken was asked about the House legislation, and said, “I can only speak for our administration and for the president. Our focus is not on saying to friends, partners: you have to choose.” – liar!

In contrast to those diplomatic words, when the Meeks bill was first marked up by the committee he chairs, ranking member and co-sponsor of the legislation Rep. Michael McCaul (R-Texas) spoke of the need to “make every state choose between doing business with the free world or with a war criminal” – the latter a reference to Russian President Vladimir Putin. – then they shouldn’t be doing business with any NATO country!

Who are the 11 senators who voted against the burn pits bill for veterans?

Who are the 11 senators who voted against the burn pits bill for veterans?

Senators Mitt Romney, Thom Tillis, Rand Paul, Tommy Tuberville, Richard Shelby, Pat Toomey, Mike Crapo, James Lankford, Mike Lee, Cynthia Lummis, and James Risch ultimately voted against the bill.

Political commentators were less surprised to see Mr Paul oppose the bill, as the libertarian frequently opposes federal spending — unless it directly benefits him.

Mr Paul said the bill would put the economy “at risk” and attempted to include an amendment to the legislation that would cut spending on foreign aid in order to offset the cost. That amendment was ultimately voted down.

Mr Paul had no problem asking for federal aid when his home state of Kentucky saw severe damage caused by tornadoes in 2021. He has regularly opposed federal aid bills for other disasters, and has previously attempted to attach amendments that reduce foreign aid spending to offset the costs of disaster relief.

Mr Tillis, Mr Lee, and Mr Lankford said they opposed the bill over fears that it would allow more people to get treatment at the VA and increase wait times for veterans seeking healthcare. While wait times are never ideal, waiting weeks or even months for treatment is still a shorter wait than simply never being eligible for healthcare.

Cut all foreign aid!